Does this sunscreen chemical promote breast cancer spread?

The link between sunscreen and cancer spread

You apply sunscreen to protect your skin, but a recent study published in Journal of Hazardous Materials suggests that a common chemical ingredient might be doing the exact opposite. Researchers found that 4-hydroxybenzophenone (4HBP), a primary metabolite of benzophenones found in many personal care products, significantly promotes the migration and invasion of breast cancer cells.

The study, which you can read here, utilized a long-term cell culture model to observe how 4HBP interacts with cancer cells. While the chemical didn't necessarily cause the cells to grow faster, it triggered the Wnt/β-catenin signaling pathway. This activation makes cancer cells more aggressive and resistant to chemotherapy. The researchers confirmed these findings in a mouse model, showing that this specific chemical exposure facilitates metastasis.

What you can do today

You don't have to wait for industry regulations to change before you take control of what you put on your body. Start by checking the ingredient labels on your sunscreens, lotions, and cosmetics for benzophenones or oxybenzone. These chemicals are common, but they aren't necessary for sun protection.

Ditching these products is a simple way to reduce your exposure to known endocrine disruptors. We have curated a list of non-toxic home alternatives that provide effective protection without the chemical baggage. Swap out your current products today and stop worrying about what is leaching into your system.

Source: Wei J, Hu Y, Wang C, Deng Y, Chen L (2026). J Hazard Mater.