The BPA Replacement BPS Stops Your Body From Burning Fat

Bisphenol S (BPS), the chemical that replaced BPA in "BPA-free" products, shuts down your body's fat-burning mechanism.

BPS Blocks Beige Fat

Researchers exposed mice to BPS at environmentally relevant levels and found it suppressed beige adipocyte formation. Beige fat cells are the ones that burn calories to generate heat. When they don't work, you gain weight more easily, according to a 2026 study in Environ Pollut.

BPS exposure reduced the key fat-burning proteins UCP1 and PGC-1-alpha. The mice developed enlarged fat cells (adipocyte hypertrophy), impaired heat generation, and couldn't tolerate cold as well as unexposed mice.

How It Works

The study found BPS binds tightly to an enzyme called CYP2E1, stabilizing it and extending its activity. This blocks the normal pathway that converts white fat cells into calorie-burning beige fat cells. When researchers knocked out CYP2E1, the BPS effect was significantly reduced.

BPS is in thermal receipt paper, canned food linings, and many products labeled "BPA-free." The switch from BPA to BPS didn't make things safer.

What You Can Do

Skip thermal receipts. Avoid canned foods with plastic linings. Don't trust "BPA-free" labels alone. Choose glass food storage. And explore non-toxic home essentials for a truly safer alternative.

Also see non-toxic kitchen essentials for safer alternatives.

Source: Liu Q, Shao Y, Xue J, et al. (2026). Environ Pollut.