BPA Is Killing Placenta Cells in Pregnant Women
NonToxCo Research
Science & Safety Team · 4/6/2026
BPA causes cell death in the placenta through a stress response called the unfolded protein response. The cells that form the barrier between mother and baby are being destroyed by a plastic chemical.
What the Study Found
A 2026 study in Reproductive Toxicology exposed BeWo trophoblast cells (placental cells) to BPA. The chemical induced IRE1-dominant endoplasmic reticulum (ER) stress, which triggered apoptosis (programmed cell death) and functional impairment of the cells.
Trophoblast cells form the outer layer of the placenta. They're responsible for implantation, nutrient transport, and hormone production. Killing them compromises the entire pregnancy.
What This Means for Pregnancy
Placental trophoblast dysfunction is linked to preeclampsia, intrauterine growth restriction, and miscarriage. If BPA is damaging these cells, it could be contributing to pregnancy complications that doctors currently can't explain.
What You Can Do
Avoid BPA during pregnancy. Ditch plastic food containers. Don't eat canned food. Use glass and stainless steel. Don't handle thermal receipt paper. Every bit of BPA you avoid is one less assault on your placenta.
Browse our non-toxic baby products for safer pregnancy options.
Also see glass food storage for safer alternatives.