PFAS Is Linked to Celiac Disease, Lupus, and IBD

If you have an autoimmune condition, or know someone who does, here's something worth reading. A 2026 scoping review in Archives of Toxicology analyzed 51 studies on PFAS exposure and autoimmunity. The majority found a link. The strongest evidence points to celiac disease and inflammatory bowel disease.

What the Review Found

Researchers from Odense University Hospital in Denmark searched five major scientific databases and analyzed every available study on PFAS and autoimmune disease. Of the 51 studies included, 33 found that higher PFAS levels were associated with increased autoimmunity risk. Nine found that even lower PFAS levels were linked to increased risk in certain conditions.

The evidence was strongest for celiac disease and IBD. There was also supporting evidence for rheumatoid arthritis, systemic lupus erythematosus, and type 1 diabetes. The immune system appears to be one of the most sensitive targets for PFAS toxicity.

Where PFAS Gets Into Your Home

PFAS isn't just a nonstick pan problem. It's in stain-resistant furniture treatments, water-repellent outdoor gear, some food packaging, and older carpet treatments. These materials release PFAS into household dust. You breathe and ingest that dust every day.

Reducing exposure means looking at the whole home. Replace PFAS-treated textiles with untreated natural alternatives. Swap nonstick cookware for stainless steel or cast iron. Browse non-toxic home essentials and non-toxic kitchen alternatives that don't use PFAS in their manufacturing or coatings.

Source: Holm-Larsen CE, Siggaard LWL, Sander SD, Østengaard L, Husby S (2026). Arch Toxicol.