Phthalates, Pregnancy Loss, and Miscarriage Risk

The Hidden Link to Pregnancy Loss

A 2026 study published in Reprod Toxicol found a direct link between MCNP—a metabolite of common phthalates—and an increased risk of pregnancy loss. Researchers analyzed data from 1445 women and discovered that higher levels of MCNP were associated with a 43% higher odd of pregnancy loss and a 50% higher risk of recurrent pregnancy loss. You can view the full study here.

How Phthalates Affect the Placenta

The study didn't just look at statistics. Researchers used animal models to show that exposure to DiDP, the parent compound of MCNP, leads to increased fetal resorption and physical changes in the placental structure. These chemicals trigger oxidative stress and inflammation, disrupting the signaling pathways necessary for a healthy pregnancy.

Reducing Your Exposure

You cannot avoid every chemical in the environment, but you can control what you bring into your home. Phthalates are commonly found in plastic food storage, personal care products, and synthetic household items. Start by swapping out soft plastics for glass or stainless steel. When you are ready to audit your nursery or kitchen, our non-toxic baby alternatives are tested to ensure you aren't bringing these specific endocrine disruptors into your living space. Small, intentional swaps are the most effective way to lower your body burden.

Source: Xu N, Hu P, Shi W, Zhou Z, Zhou X (2026). Reprod Toxicol.