Can bisphenol S in 'BPA-free' products harm your brain and nervous system?

What's actually in it

Bisphenol S (BPS) is the chemical used to replace BPA in products marketed as "BPA-free." It shows up in thermal receipt paper, food cans, plastic water bottles, baby bottles, and food storage containers. BPS was supposed to be safer than BPA, but it has a very similar chemical structure and acts on many of the same biological pathways.

What the research says

A 2026 review in Mol Neurobiol gathered evidence from multiple studies on how BPS affects the brain and nervous system. The review found that BPS can damage neurons, disrupt brain signaling, and alter brain development. It works through several mechanisms including oxidative stress, inflammation, and interference with estrogen receptors in the brain.

The review concluded that BPS may be just as harmful to the nervous system as BPA. Products labeled "BPA-free" aren't necessarily safer if they contain BPS instead.

Don't trust "BPA-free" labels as a guarantee of safety. Choose glass, stainless steel, or ceramic for food and drink storage. Decline paper receipts when possible, since thermal paper is a major source of BPS exposure.