Can prenatal chlorpyrifos exposure have lasting effects on your child's brain chemistry?
Yes. A 2025 study found gestational chlorpyrifos exposure causes lasting increases in neuronal activity and serotonin receptor changes that persist into adulthood.
What's actually in it
Chlorpyrifos is an organophosphate pesticide that was widely used in homes and on food crops. Though residential use is now restricted in the U.S., residues persist in food and in homes treated years ago. It crosses the placenta and reaches the developing brain.
What the research says
A 2025 study in eNeuro found that gestational chlorpyrifos exposure causes lasting increases in neuronal activity and altered serotonergic receptor expression that persist into adulthood. These brain chemistry changes were still detectable long after the original exposure.
Buy organic produce, especially for fruits and vegetables on the "Dirty Dozen" list. Wash all produce thoroughly.
The research at a glance
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